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Metabolic Diseases

Date: 2015-10-16

  High fat diet (HFD) induced obesity mice (DIO mice)
  ob/ob mice, db/db mice
  HFD induced DIO Rats


HFD induced mouse obesity at C57BL/6 male mice
  HFD (60% kcal)-induced DIO mice with diabetes
  ob/ob, db/db mice with diabetes
Diabetic Complication
  Diabetic nephropathy in db/db mice, DIO mice
  Peripheral vascular disease (PVD) in db/db mice, DIO mice
  Diabetic muscle amyotrophy (myopathy) in db/db mice, DIO mice

Long term DIO induces a obesity-related glomerulopathy HFD induces
mouse obesity at C57BL/6 male mice for 18 weeks (A&B) and 30 weeks (C&D).
Glomerulus enlarges with partial Glomerular mesenchymal cell hyperplasia at 30
weeks as compared with that at 18 weeks.
High fat diet/ high cholesterol/ high fructose diet models in rodents and hamster

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