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Address:699-18 XuanWu Avenue, Nanjing, Jiangsu, China
Phone:86-025-85560000-1588 Mail: info@kcibiotech.com; zhuangyongjie@kcibiotech.com;

Product Name:

Cardiovascular diseases

Date: 2015-10-16

Cardiovascular diseases
  Acute ischemia, ischemia reperfusion injury models
 
Stroke models
  Ischemic model (permanent MCAO) in rodents
  Ischemic reperfusion model (transient MCAO) in rodents
  Hemorrhagic model (CIH) in rodents


 

Rat MCAO model

Brain infarct size at different MCAO condition

 
Acute myocardial infarction (AMI) models
  Permanent / transient AMI in rodents, rabbit and pig
  AMI induced heart failure model in rodents and rabbit

 

Rat AMI model and assessment Myocardial infarct size at different acute ischemia condition


Rabbit AMI model and the changes in the infarct size and ECG at ischemia and reperfusion points


Pig AMI model and the changes in the infarct size at day 5 of reperfusion

 

Peripheral vascular disease (PVD)
  Limb ischemia reperfusion models in rodents
 
Atherosclerosis models
  Endothelial cell denudation induced intimal thickness model in rodents
 


Low flow induces carotid artery intimal thickness in mice model

 

  HFD + cholesterol induced atherosclerosis model in hamster and rabbits
  Blood flow induced intimal thickness model in rabbits

 

Arterial venous fistula (AVF) creation


High flow induces carotid artery dilation and remodeling


High flow induces arterial remodeling, histologic evaluation


Changes in blood flow (High flow to low flow) induces arterial intimal
  thickness, one cycle of flow change induces one layer of intimal thickness.


Change in blood flow (High flow to low flow) induces endothelial cell apoptosis (SEM and TEM examination).

 

Collagenase induced abdominal aortic aneurysm (AAA) model in rodents

 

PPE induced abdominal aortic aneurysm (AAA) model in rats.


Histologic examination of AAA in rat PPE model

PPE induced AAA model in mice.


High flow regulates AAA size in PPE induced AAA model in mice.


Gross examination of PPE induced mouse AAA model.


Histologic examination of PPE induced mouse AAA model.


IF examination of PPE induced mouse AAA model


Diagrams of AAA with endoleaks


Diagrams of endoleak model creation in rabbits


Procedures of stent graft implantation model


Pathologic examination of stent graft implantation model

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