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Inflammation and Autoimmune Diseases

Date: 2017-09-05

Airway Inflammation
  LPS-induced acute lung inflammation in rodents
Experimental allergic encephalomyelitis (EAE)
  MBP induced acute EAE in Lewis rats
  PLP139-151 induced EAE in SJL/J mice
  MOG35-55 induced EAE in C57BL/6 mice
Lung Fibrosis
  Bleomycin induced lung fibrosis model in mice


Bleomycin induced mouse lung fibrosis model

Rheumatoid Arthritis
  Adjuvant induced arthritis (AIA) in rats
  Collagen type II induced arthritis (CIA) in rodents

Morphology Changes in rat CIA model. Normal joint (A) and joint with arthritis (B);
inflammatory cell infiltration (C: macrophage (CD68); D: lymphocyte (CD3)).
Osteoarthritis (OA)
  MIA induced OA in rats
Inflammatory Bowel Disease (IBD)
  DSS induced colitis in C57BL/c mice
  TNBS/DNBS induced colitis in rodents


Morphology Changes of TNBS-induced acute inflammatory bowel disease
(IBD) model in mouse with histologic examination A: normal mouse colon; B&C:
IBD (H&E) showing mucosa ulceration and transmural inflammatory cell infiltration.

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